Biocompatibility, Corrosion Behavior, And Ion Release Characteristics Of Mg–Zn Alloys For Biodegradable Urological Stents Umida Abdujabborova
Keywords:
Magnesium Alloys, Biodegradable Stents, UrologyAbstract
The development of biodegradable metallic materials has become a major focus in modern biomedical engineering due to their ability to provide temporary mechanical support while eliminating the need for secondary surgical removal. Magnesium-based alloys have emerged as promising candidates for biodegradable implants owing to their favorable mechanical properties, biodegradability, and biological compatibility. The present study evaluates the corrosion behavior, ion release characteristics, and potential biocompatibility of Mg–Zn alloys intended for application as biodegradable urological stents. Particular attention is given to Mg–4Zn alloys under simulated physiological and acidic conditions. In vitro investigations demonstrated that the concentrations of released Mg²⁺ and Zn²⁺ ions remained within biologically acceptable ranges throughout the experimental period. Furthermore, Mg–4Zn alloys maintained structural integrity for up to 30 days even under conditions of elevated acidity, which simulates pathological urinary environments
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